When closing a pharmacy and you have leftover DEA 222 forms, what must you do with them?

• A. Return to DEA
• B. Keep for records
• C. Destroy them
• D. Sell to the new owner

Answer: (A)

When wrapping up a pharmacy, the Forms 222 used to order Schedule I and II drugs are government paperwork that must be surrendered rather than kept or discarded. Unused (leftover) Form 222s should be returned to the DEA so there’s a clean, auditable end to the registration and ordering authority. Keeping, destroying, or transferring them to a new owner creates a risk of fraudulent or improper orders and leaves the DEA with unresolved records. In practice, contact the DEA Diversion Control Division to arrange the return and keep copies of the submission for your records. If any forms were partially used, you would generally void the unused portions before returning, per the DEA’s guidance.