What is the beyond-use date for USP 795 compounded non-preserved aqueous preparations?

• A. 7 days
• B. 28 days
• C. 14 days
• D. 35 days

Answer: (C)

The key idea is how long you can safely store a compounded non-preserved aqueous preparation before it must be used or discarded. Water-containing products without antimicrobial preservatives are at higher risk for microbial growth, so the beyond-use date is limited to a short period to protect safety and quality. For these non-preserved aqueous formulations under USP 795, the standard guidance is 14 days, typically with refrigeration to further reduce microbial risk. Without a preservative, extending beyond this window isn’t supported by the guidelines, which is why 14 days is the correct choice. The other timeframes would either imply a longer shelf life without a preservative or apply to different types of formulations.