How long do you have to notify the DEA of missing controlled substances?

• A. Within 1 hour
• B. Within 1 day
• C. Within 1 business day
• D. Within 3 days

Answer: (C)

When controlled substances go missing, prompt reporting to the DEA is required to support a timely investigation and prevent further diversion. The rule is to notify within one business day of discovery. This means you don’t have to react to the moment you notice the loss during off-hours or on a weekend with a clock-ticking urgency, but you do need to report it by the next business day. In practice, this often means making an initial report by phone or other immediate notice and then submitting the formal documentation (such as the required DEA form) per DEA instructions.

This 1-business-day window strikes a balance between urgency and the realities of operating on a schedule. Reporting too slowly could hinder enforcement and accountability, while requiring report within hours would be impractical in many settings. The emphasis is on rapid, documented notification to support safety and compliance.

You should also notify local law enforcement immediately and preserve all records related to the loss.