Collaborative practice agreements must be in writing and signed by which parties?

• A. Prescriber(s) and Pharmacist(s).
• B. Only the Pharmacist.
• C. Only the Prescriber.
• D. The patient.

Answer: (C)

The key idea here is that a collaborative practice arrangement is an authorization issued by the prescriber that allows a pharmacist to provide certain patient-care activities under a defined protocol. The essential act that makes this arrangement valid is the prescriber’s signature, which confirms the prescriber’s authority to grant the pharmacist the expanded scope of practice. The patient is not typically required to sign the CPA, since they are the recipient of care, not a signatory to the governance of the collaboration. The pharmacist’s signature may appear to acknowledge the agreement in some processes, but the legally decisive endorsement is the prescriber’s, which is why the option with the prescriber signing only is the best fit for this scenario.