Can controlled substance prescriptions be sent electronically?

• A. No
• B. Yes, for C-II only
• C. Yes, for non-controlled substances only
• D. Yes, for all controlled substances, including C-II

Answer: (D)

Electronic prescribing of controlled substances is allowed when the prescriber uses an approved electronic prescribing system with proper security. The relevant program (EPCS) enables sending prescriptions for all controlled substances, including the most tightly regulated ones, to pharmacies once the system is enrolled and the prescriber uses two-factor authentication. This setup creates a verifiable audit trail, reduces the chance of prescription forgery, and helps ensure accurate dispensing. While some states may add specific rules or waivers, the general practice supports electronic transmission for the full range of controlled substances, not just non-controlled drugs or a subset.