After an electronic prescription is transmitted, who can change it?

• A. The physician only
• B. Nothing can be changed by the physician
• C. Pharmacist can call and make changes
• D. The patient can request changes

Answer: (C)

When an electronic prescription has reached the pharmacy, the pharmacist is the one who can initiate changes by contacting the prescriber. Real‑time communication between pharmacy and clinician lets the pharmacist flag potential issues, confirm instructions, or request adjustments to dose, formulation, or drug selection. Any changes are made only with the prescriber’s authorization, and the system updates accordingly so the patient gets the corrected prescription.

This reflects how safety and accuracy are maintained in e‑prescribing: the pharmacist can discuss and propose changes, and the prescriber approves them. The physician isn’t the only one who can alter the order after transmission, and the patient can request changes but cannot directly modify the prescription—those requests need to go through the prescriber and the pharmacist.